This study used the Ricardian approach to examine the economic impacts of climate change on crop production in the coastal provinces of the Vietnam Mekong Delta. The authors conducted a regression analysis of the net farm revenue against climate, soil, inundation, irrigation, and other socioeconomic variables in order to examine their effects on the variability of net farm revenues. Results showed that an increase in temperature has a negative effect on net farm revenues, while an increase in precipitation has a positive effect. Net crop revenue per hectare would fall by approximately VND 180,000–VND 200,000 in 2050; and by VND 300,000–VND 1,600,000 by 2100. This study also identified the major methods used by farmers in the coastal provinces of the Vietnam Mekong Delta in order to adapt to climate change and the factors that affect their choices of adaptation measures. The adaptation methods identified include using different crop varieties, changing farmers’ planting schedule, intensifying irrigation, and adopting crop diversification. The results of the model indicate that level of education, gender, age, household size, minority, participating in organization, information on climate change and temperature during the rainy season influence farmers’ choices.