Policy analysis matrices are developed and used to derive domestic resource cost coefficients for different catfish farm production regions in the United States. The results show that U.S. catfish producers were losing their comparative advantage positions during the study period considered. An import tariff improves the industry's comparative advantage position, but may not increase its market profitability. Higher efficiency in feed usage, and higher market prices paid to producers through promotional efforts are essential to the U.S. catfish industry.